Science behind
the perspective.

Puneet Tyagi

Exploration of Development Parameters for IgG Microspheres Using an Automated Platform for High-Throughput Formulation Screening

P. Tyagi et al.

Pharmaceuticals, 2026; 19(8): 1203

Puneet Tyagi

Current status and prospect for future advancements of long-acting antibody formulations

P. Tyagi et al.

Expert Opinion on Drug Delivery, 2023

Puneet Tyagi

Systems Biology and Peptide Engineering to Overcome Absorption Barriers for Oral Peptide Delivery: Dosage Form Optimization Case Study Preceding Clinical Translation

P. Tyagi et al.

Pharmaceutics, 2023; 15: 2436

Puneet Tyagi

A catch-and-release nano-based gene delivery system

C. Franck, A. B. Popov, I. Ahmed, R. E. Hewitt, L. Franslau, P. Tyagi, L. Fruk

Nanoscale Horizons, 2023, 8, 1588

Puneet Tyagi

Injectable Biodegradable Silica Depot: Two Months of Sustained Release of the Blood Glucose Lowering Peptide, Pramlintide

P. Tyagi et al.

Pharmaceutics, 2022; 14(3): 553

Puneet Tyagi

Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease

S. Pechenov, J. Revell, S. Will, J. Naylor, P. Tyagi et al.

Scientific Reports, 2021; 11: 22521

Puneet Tyagi · Ruchit Trivedi

Targeted Oral Peptide Delivery Using Multi-unit Particulates: Drug and Permeation Enhancer Layering Approach

P. Tyagi, et al.

J. Of Controlled Rel., 2021; 338: 784-791

Puneet Tyagi

Biopolymer‐based Carriers for DNA Vaccine Design

C.O. Franck, L Fanslau, A Bistrovic Popov, P. Tyagi

Angewandte Chemie, 2021

Puneet Tyagi

Harnessing the nano-bio interface: Application of membrane coating to long acting silica particles

P. Tyagi

Eur. J. Pharm. Biopharm., 2020, 158:382-389

Puneet Tyagi

Evaluation of Pyrrolobenzodiazepine loaded Nanoparticles: A potential targeted drug delivery approach

P. Tyagi, et al.

J. Pharm. Sci., 2019, 108 (4):1590–1597

Puneet Tyagi

Oral peptide delivery: Translational challenges due to physiological effects

P. Tyagi, et al.

J. Of Controlled Rel., 2018; 287:167-176

Puneet Tyagi

Nanotherapeutics in oral and parenteral drug delivery: Key learnings and future outlooks as we think small

P. Tyagi, A. Subramony

J. Of Controlled Rel., 2018; 272:159-168

Puneet Tyagi

Macromolecule nanotherapeutics: approaches and challenges

P. Tyagi, J.L. Santos

Drug Discovery Today, 2018;23(5):1053-1061

Puneet Tyagi

Silica microparticles for sustained zero-order release of an anti-CD40L antibody

P. Tyagi, et al.

Drug Del. and Transl. Res., 2018;8(2):368-374

Ruchit Trivedi

The chemomodulatory effects of glufosfamide on docetaxel cytotoxicity in prostate cancer cells

Attia, R.T., Tolba, M.F., Trivedi, R., Tadros, M.G., Arafa, H.M., Abdel-Naim, A.B.

PeerJ. 2016; 4: e2168

Puneet Tyagi

Nanoparticle-mediated expression of a wnt pathway inhibitor ameliorates ocular neovascularization

Z. Wang, R. Cheng, K. Lee, P. Tyagi, L. Ding, U. Kompella, J. Chen, X. Xu, J. Ma

Arterioscler Thromb Vasc Biol. 2015;35(4):855-64

Ruchit Trivedi

Preventing Damage to Freeze-Sensitive Antigen Formulated with an Aluminum-Containing Adjuvant is Insufficient for Maintaining Vaccine Efficacy

Clapp, T.M., Munks, M., Trivedi, R., Kompella, U.B., Jones-Braun, L.

Vaccine. 2014 Jun 24; 32(30): 3765–3771

Puneet Tyagi

RGD-targeted nanoparticles delivering Flt23k intraceptor-plasmids effectively treat primate and murine models of AMD

L. Luo, Y. Hirano, X. Zhang, P. Barabas, P. Tyagi, et al.

ACS Nano, 2013; 7(4): 3264–3275

Puneet Tyagi

Light activated, In situ Forming Gel for Sustained Suprachoroidal Delivery of Bevacizumab

P. Tyagi, M. Barros, J. Stansbury, U. Kompella

Molecular Pharmaceutics, 2013.

Puneet Tyagi

Supercritical Fluid Technology Based Large Porous Celecoxib-PLGA Microparticles Do Not Induce Pulmonary Fibrosis and Sustain Drug Delivery and Efficacy for Several Weeks Following A Single Dose

D. Dhanda, P. Tyagi, U. Kompella

Journal of Controlled Release,2013;168(3), 239–250

Ruchit Trivedi

Pirfenidone nanoparticles improve corneal wound healing and prevent scarring following alkali burn

Chowdhury, S., Guha, R., Trivedi, R., Kompella, U.B., Konar, A., Hazra, S.

PLoS ONE. 2013; 8(8): e70528

Puneet Tyagi

Acidic nanoparticles to restore lysosomal pH and degradative function in compromised RPE cells

G. Baltazar, S. Guha, A. Laties, P. Tyagi, U. Kompella, C. Mitchell

PLoS One, 2012; 7(12): e49635.

Puneet Tyagi

Comparison of Suprachoroidal Drug Delivery with Subconjunctival and Intravitreal Routes using Noninvasive Fluorophotometry

P. Tyagi, R. Kadam, U. Kompella

PLoS One, 2012; 7(10): e48188.

Puneet Tyagi

Potential therapies for vesicant-inflicted ocular injuries

N. Tewari-Singh, A. Jain, S. Inturi, D. Ammar, C. Agarwal, P. Tyagi, U. Kompella, R. Enzenauer, J. Petrash, R. Agarwal

Toxicology and Applied Pharmacology. 2012; 264(1): 23-31

Puneet Tyagi

Influence of choroidal neovascularization and biodegradable polymeric particle size on transscleral sustained delivery of triamcinolone acetonide

P. Tyagi*, R. Kadam*, H. Edelhauser, U. Kompella

Int. J. Pharm.2012;434(1-2):140-147 [* equal contributing authors]

Puneet Tyagi

A hybrid dendrimer gel/PLGA nanoparticle platform sustains one week antiglaucoma effects following one-time topical instillation

H. Yang, P. Tyagi, R Kadam, C. Holden, U. Kompella

ACS Nano. 2012; 6(9):7595-7606

Puneet Tyagi

Flt23k Nanoparticles Enhance Graft Survival in a Murine Penetrating Keratoplasty Model

H. Uehara, Y. Cho, J. Young, P. Tyagi, U. Kompella, L. Luo, B. Archer, B. Ambati, 

Invest Ophthalmol Vis Sci. 2012; 53(4):2328-2336.

Puneet Tyagi

Polyamidoamine dendrimer hydrogel for ocular drug delivery: In vitro and ex vivo evaluation of brimonidine and timolol maleate dendrimer hydrogel formulations

P. Tyagi*, C. Holden*, A. Thakur, R. Kadam, G. Jadhav, U. Kompella, H. Yang

Nanomedicine: Nanotechnology, Biology and Medicine, 2012;8(5):776-783.[* equal contributing authors]

Ruchit Trivedi

Local delivery of biodegradable pirfenidone nanoparticles ameliorates bleomycin-induced pulmonary fibrosis in mice

Trivedi, R., Redente, E.F., Thakur, A., Riches, D.W., Kompella, U.B.

Nanotechnology. 2012 Dec 21; 23(50): 505101

Recommended by Faculty of 1000

Puneet Tyagi

Anti-inflammatory and anti-angiogenic effects of nanoparticle-mediated delivery of a natural angiogenic inhibitor

J. Jin, K. Park, Y. Hu, X. Xu, Z. Zheng, P. Tyagi, U. Kompella

Invest Ophthalmol Vis Sci. 2011; 52(9):6230-7.

Ruchit Trivedi

RGD-Functionalized STAT1 siRNA Nanoparticles Regress Rheumatoid Arthritis in a Mouse Model

Scheinman, R., Trivedi, R., Vermilion, S., Kompella, U.B.

Nanomedicine (Lond). 2011 Dec; 6(10): 1669–1682

Ruchit Trivedi

Delivery of SAR 1118 to Retina Via Ophthalmic Drops and its Effectiveness in Reduction of Retinal Leukostasis and Vascular Leakiness in Rat Streptozotocin (STZ) Model of Diabetic Retinopathy (DR)

Rao, V.R., Prescott, E., Shelke, N., Trivedi, R., Thomas, P., Struble, C., Gadek, T., O’Neill, C.A., Kompella, U.B.

Investigative Ophthalmology and Visual Science. 2010; 51(10): 5198–5204

Ruchit Trivedi

Nanomicellar formulations for sustained drug delivery: Strategies and underlying principles

Trivedi, R., Kompella, U.B.

Nanomedicine (Lond). 2010; 5(3): 485–505

Ruchit Trivedi

Targeted drug and gene delivery systems for lung cancer therapy

Sundaram, S., Trivedi, R., Durairaj, C., Ramesh, R., Ambati, B.K., Kompella, U.B.

Clinical Cancer Research. 2009; 15(23): 7299–7308

Puneet Tyagi

Development and evaluation of gastroretentive drug delivery system for a low absorption window drug celecoxib

J. Ali, P. Tyagi, A. Ahuja, S. Baboota and S. Hasan

PDA Journal of Pharmaceutical Science & Technology 2007;61(1): 1-9.

Puneet Tyagi

Systemic Delivery of Genetic Material by non-viral vectors

P. Tyagi, J. Ali, A. Ahuja, S. Baboota and R. Khar

Indian Journal of Pharmaceutical Sciences. 2004; 66(3): 272-277.